Pantoprazole: Uses And Side Effects You Should Know

Stomach acid might be problematic. Excess of it could typically result in heartburn and acid reflux disease, ultimately inflicting severe illnesses like gastroesophageal reflux illness (GERD). This is the place Pantoprazole comes into the image. It is an oral pill that reduces the quantity of acid produced in your physique. In this text, we’ll focus on this drug in higher element. Keep studying.

Table of Contents

  • What Is Pantoprazole? How Does It Work?
  • What Are The Uses Of Pantoprazole?
  • What Are The Side Effects Of Pantoprazole?

What Is Pantoprazole? How Does It Work?

Pantoprazole is a prescription drug that’s very often used as an oral pill. It additionally is offered as an oral liquid suspension or within the intravenous kind (the place a healthcare supplier injects it into your system).

It works to cut back the quantity of acid your physique produces. This may also help deal with illnesses like GERD. The drug works by shutting off the acid-pumping cells in your stomach. This method, it reduces the quantity of abdomen acid and presents reduction from associated illnesses.

Let’s take a deeper look into how this drug may also help you.

What Are The Uses Of Pantoprazole?

1. Fights GERD

A research exhibits that oral Pantoprazole might enhance the standard of life in folks with GERD (1). The drug can be discovered to be effectively tolerated amongst sufferers. This is very true within the older inhabitants, which is at the next danger of creating GERD.

In one other research, Pantoprazole confirmed wonderful reduction and was effectively tolerated by topics. Throughout all the research, greater than 90% of the sufferers confirmed enchancment with none antagonistic results. And simply four sufferers had discontinued the remedy attributable to antagonistic results (2).

Pantoprazole belongs to a category of medication often known as proton pump inhibitors (PPIs). These are noticed to be the best remedy for GERD (three). GERD happens when the refluxed acid and pepsin are available in contact with the esophageal mucosa.

2. Helps Treat Erosive Esophagitis

Though just like GERD, this situation is characterised by an infected esophagus. This occurs because of the improve within the variety of a kind of white blood cells within the lining of the esophageal wall. Thanks to its exercise as a proton pump inhibitor, Pantoprazole generally is a protected and efficient remedy for erosive esophagitis (four).

GERD, if left untreated, can typically result in erosive esophagitis. This means treating the previous can eradicate your danger of creating the latter.

three. Helps Cure Helicobacter pylori Infection

Helicobacter pylori (micro organism) can enter your physique by way of the digestive tract and dwell there for years, resulting in extreme ulcers within the lining of your abdomen and small gut. The an infection may result in abdomen most cancers in some folks. But Pantoprazole might treatment this an infection.

In a German research, of the 52 sufferers handled with Pantoprazole, 47 had proven nice decline within the ranges of the Helicobacter pylori an infection (5).

four. Aids Treatment Of Zollinger-Ellison Syndrome

This is a situation during which a number of tumors kind in your pancreas or the higher a part of your small gut. These tumors secrete gastrin (a hormone) in massive quantities, inflicting your abdomen to supply extra acid. Eventually, all of this results in peptic ulcers and even diarrhea.

Studies present that Pantoprazole, when administered in doses between 40 and 160 mg, can management acid hypersecretion in sufferers with Zollinger-Ellison syndrome (6). In the research, Pantoprazole was additionally discovered to be effectively tolerated and triggered minimal antagonistic results.

5. Relieves Persistent Cough

Studies on proton pump inhibitors present some attention-grabbing outcomes. Cough related to GERD can present nice enchancment with PPIs (7). Persistent cough is usually attributable to untreated GERD. Since Pantoprazole performs an vital position in treating GERD, it additionally helps relieve the related cough (eight).

These are the makes use of of Pantoprazole. Its exercise boils all the way down to decreasing extra abdomen acid. Given that GERD and the associated illnesses are on the rise at the moment, Pantoprazole serves as the perfect drug to take care of these points.

But wait, earlier than we go forward singing praises of this prescription drugs, let’s check out the opposite facet too.

What Are The Side Effects Of Pantoprazole?

Some widespread unintended effects embody diarrhea, headache, gasoline, dizziness, joint ache, and nausea or vomiting (9). If any of those persist, please seek the advice of your physician.

Serious unintended effects of Pantoprazole embody:

  • Magnesium Deficiency

Using proton pump inhibitors, like Pantoprazole, for greater than three months in a row could cause magnesium deficiency (10). Symptoms embody tremors, muscle weak spot, seizures, and dizziness.

  • Vitamin B12 Deficiency

Using Pantoprazole for greater than three years could make it troublesome to your physique to soak up vitamin B12. Symptoms embody nervousness, numbness, improper muscular coordination, and adjustments in your menstrual cycle. Studies present that the nonjudicious use of such proton pump inhibitors can result in nutrient deficiencies, together with that of vitamin B12 (11).

  • Other Serious Side Effects

These embody bone fractures and kidney injury (characterised by adjustments in urination and ache in your facet and again).

  • Drug Interactions

Pantoprazole might work together with sure medicine. These embody HIV medicine like Atazanavir and Nelfinavir, anticoagulants like Warfarin, and medicines affected by abdomen pH like Ketoconazole, Ampicillin, and iron salts.

If you expertise any of those severe unintended effects, please seek the advice of your physician immediately.


Pantoprazole works nice for GERD and different associated points. But do test along with your physician relating to this – extra so if you’re already on some other remedy.

Expert’s Answers For Readers’ Questions

What is the dosage of Pantoprazole?

The dosage can range from 20 mg to 40 mg. But, this will depend on your health situation. Hence, it’s best to test along with your physician.

What is the most effective time to take Pantoprazole?

Ideally, you need to take it as soon as a day, very first thing within the morning. If you might be to take it twice a day, you may take as soon as within the morning and as soon as within the night. Taking Pantoprazole at the very least an hour earlier than meals works finest.

Can you are taking antacids with Pantoprazole?

Yes, you may. But to be on the protected facet, please test along with your physician.

How lengthy does Pantoprazole take to work?

You ought to begin feeling higher in as little as 2 to three days. And for the remedy to point out its full results, it would take as much as four weeks.

What medicine are just like Pantoprazole?

As mentioned, Pantoprazole belongs to a category of medication known as proton pump inhibitors. Other comparable medicine embody Lansoprazole, Rabeprazole, and Omeprazole.

Is there a generic model for Pantoprazole?

Yes, and it’s known as Protonix. It is offered with the energetic ingredient pantoprazole.

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